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2-(4-N-PROPYLPHENYL)PROPIONIC ACID

2-(4-propylphenyl)propanoic acid

CAS: 3585-47-5

Molecular Formula: C12H18O

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2-(4-N-PROPYLPHENYL)PROPIONIC ACID - Names and Identifiers

Name 2-(4-propylphenyl)propanoic acid
Synonyms Ibuprofen Impurity
p-Propylhydratropic Acid
2-(4-propylphenyl)propanoic acid
α-Methyl-4-propylphenylacetic Acid
2-(4-N-PROPYLPHENYL)PROPIONIC ACID
a-Methyl-4-propylphenylacetic Acid
a-Methyl-4-propylbenzeneacetic Acid
α-Methyl-4-propylbenzeneacetic Acid
(2RS)-2-(4-N-PROPYLPHENYL)PROPANOIC ACID
CAS 3585-47-5

2-(4-N-PROPYLPHENYL)PROPIONIC ACID - Physico-chemical Properties

Molecular FormulaC12H18O
Molar Mass178.27072
Density1.047±0.06 g/cm3(Predicted)
Boling Point310.5±11.0 °C(Predicted)
Solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
AppearanceSolid
ColorWhite to Off-White Low-Melting
pKa4.44±0.10(Predicted)
Storage ConditionRefrigerator
Physical and Chemical PropertiesBioactive Ibuprofen impurity 1 is a Ibuprofen impurity. Ibuprofen is an inhibitor of COX-1 and COX-2, with IC50 values of 13 μM and 370 μM respectively, and has anti-inflammatory activity.

2-(4-N-PROPYLPHENYL)PROPIONIC ACID - Introduction

2-(4-propylphenyl)propanoic acid is an organic compound with the chemical formula C12H16O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-(4-propylphenyl)propanoic acid is a colorless to light yellow solid.
-Solubility: It can be dissolved in organic solvents such as ethanol, methanol and dichloromethane.
-Storage stability: 2-(4-propylphenyl)propanoic acid should be stored in a dry, cool place. Avoid contact with oxidant, strong acid and strong alkali.

Use:
-Chemical synthesis: 2-(4-propylphenyl)propanoic acid can be used as raw materials or intermediates in organic synthesis. It can be used to synthesize drugs, dyes, lubricants and other compounds.
-Catalyst: It can also be used as one of the ligands or catalysts to participate in the synthesis reaction of the catalyst.
-Laboratory research: 2-(4-propylphenyl)propanoic acid can be used as a commonly used reagent in chemical laboratories for various organic synthesis and Reaction Research.

Method:
- 2-(4-propylphenyl)propanoic acid can be prepared by condensation reaction of phenylacetylene and propionaldehyde, and then carbonyl oxidation reaction under alkaline conditions.

Safety Information:
- 2-(4-propylphenyl)propanoic acid is a chemical. Personal protective measures should be taken when using it, including wearing safety glasses and gloves.
-Its specific hazards still need to be assessed and confirmed according to national and regional regulations.
-During use and storage, it is necessary to comply with relevant safety procedures to prevent accidents such as fires, explosions, and leakage of hazardous substances.
-If ingestion or contact with 2-(4-propylphenyl)propanoic acid, seek medical attention immediately and provide relevant information.
Last Update:2024-04-09 02:00:52
2-(4-N-PROPYLPHENYL)PROPIONIC ACID
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2-(4-N-PROPYLPHENYL)PROPIONIC ACID
(E)-3-(4-氟苯基)丙烯酸乙酯
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